Diverse as these tales are, what connects them is the powerful voice of a born storyteller. William Gay expertly sets these conflicted people who make bad choices in life and love against lush back-country scenery, and somehow manages to defy moral logic as we grow to love his characters for the weight of their human errors. In these pages readers meet old man Meecham, who escapes from his new nursing home only to find his son has rented their homestead to "white trash" Quincy Nell Qualls, who not only falls in love with the town lothario but, pregnant, is faced with an inescapable end when he abandons her Finis and Doneita Beasley, whose forty-year marriage is broken up by a dead dog Bobby Pettijohn, who is awakened in the middle of the night by the noise and lights of a search party looking for clues after a body is discovered in his backwoods. His debut collection, I Hate to See That Evening Sun Go Down, brings together what Gay's dedicated readers are eager for and what new readers will find the perfect introduction to his world: thirteen stories that are mined from this same fertile soil teeming with the grizzled, everyday folk that Gay is famous for bringing to life. Warren Welch (That’s Not Poetry)-that are sure to tingle your spine and make you think twice about sleeping with the lights off tonight. WITCHES OF THE WOOD is a collection of eight short stories from authors born and raised in Appalachia-including bestselling young adult novelist Bekah Harris (Iron Crown Faerie Tales) and social media sensation J. Sometimes, the scariest things in the woods come from within us. Brooklyn and others and an Apple Books and Oprah Magazine best book of January 2020. These are the tales that sometimes teach us there are scarier things in the world than ghosts and haints. Appalachia is a region with fairly poor farmland outside of the river valleys, river valleys that are prone to flooding, rivers that difficult to navigate by barge (compared to the Mississippi), and mountains that are difficult to build railroads and highways through. Her first book of nonfiction, The Third Rainbow Girl: The Long Life of a Double Murder in Appalachia (Hachette Books ) has been named an Indie Next pick for February 2020, a most anticipated book from The Millions, Electric Literature, Vol.1. ![]() It’s those stories-like the ones in this collection-that beckon you into a world of dark mystery and unadulterated horror. ![]() Sometimes, what you find at the end of a dark path, or within an abandoned cabin, or at the top of an old, decaying staircase, will scare some sense into you and equip you with a healthy dose of fear and caution as you walk about your daily life.Īnd then there are times when the stories seem so real, a little voice inside you urges you to turn back, rather than turn the page. Sometimes the absurd and the unexplained come together to teach morals and lessons that are passed down through the years. ![]() Sometimes, these devilishly wicked tales are little more than innocent make-believe. In the hills of Appalachia, folks tell all kinds of stories to keep the children in line.
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![]() ![]() Raven, New York, pp 199–233īertilsson L, Tuck JR, Siwers B (1980) Biochemical effects of Zimelidine in man. In: DJ McGinty, Drucker-Collin R, Morrison A, Parmeggiani P (eds) Brain mechanisms of sleep. Pharmacol Biochem Behav 5:599–602.īaker T, Dement WC (1985) Canine narcolepsy-cataplexy syndrome evidence for an inherited monoaminergic-cholinergic imbalance. Synapse 6:33–44īabcock DA, Narver EL, Dement WC, Mitler MM (1976) Effects of imipramine, chlorimipramine, and fluoxetine on cataplexy in dogs. Eur J Pharmacol 166:493–504Īppel NM, Mitchell WMM, Contrera JF, De Souza EB (1990) Effects of high dose fenfluramine treatment on monoamine uptake sites in rat brain: assessment using quantitative autoradiography. GBR 12909: selectivity and molecular mechanism of action. Neurology 42:34–43Īndersen PH (1989) The dopamine uptake inhibitor. Our findings also demonstrate that canine narcolepsy is a useful tool in assessing the pharmacological specificity of antidepressant drugs.Īldrich M(1992) Narcolepsy. Our results demonstrate the preferential involvement of adrenergic systems in the control of cataplexy and, presumably, REM sleep atonia. All compounds affecting noradrenergic transmission completely suppressed canine cataplexy at low doses in all dogs tested, whereas compounds which predominantly modified serotoninergic and dopaminergic transmission were either inactive or partially active at high doses. Some additional compounds interesting clinically but with less pharmacological selectivity, i.e., cocaine, dextroamphetamine, methylphenidate, nomifensine and pemoline, were also included in the study. A total of 14 compounds acting on the adrenergic (desipramine, nisoxetine, nortriptyline, tomoxetine, viloxazine), serotoninergic (fenfluramine, fluoxetine, indalpine, paroxetine, zimelidine) and dopaminergic (amfonelic acid, amineptine, bupropion, GBR 12909) systems were tested. ![]() ![]() In order to determine which monoamine is selectively involved in the therapeutic effect of these compounds, we examined the effects of selective monoamine uptake inhibitors and release enhancers on cataplexy using a canine model of the human disorder. Both stimulant and antidepressant drugs presynaptically enhance monoaminergic transmission but both classes of compounds lack pharmacological specificity. Cell 98, 365–376.Narcolepsy is currently treated with antidepressants to control REM-related symptoms such as cataplexy and with amphetamine-like stimulants for the management of sleepiness. The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene. Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P.J., Nishino, S., and Mignot, E. Identification and Functional Analysis of Mutations in the Hypocretin (Orexin) Genes of Narcoleptic Canines. Hungs, M., Fan, J., Lin, L., Lin, X., Maki, R.A., and Mignot, E. Small-breed dogs seem to be more severely affected. Symptoms usually appear by the dog’s 6 months of age. Predisposed breeds include the Labrador Retriever, Poodle, Dachshund and the Doberman Pinscher. Sudden loss of muscle tone triggered mainly by positive emotions that share some physiological similarities with REM sleep atonia, called cataplexy is the most valuable clinical feature used to diagnose narcolepsy. Narcolepsy has been diagnosed in many breeds and has an established hereditary component. Symptoms appear suddenly, and the recovery is spontanious as well. Dog narcolepsy Labrador type is a disabling sleep disorder characterized by daytime sleepiness, sleep fragmentation, striking transitions from wakefulness into rapid eye movement (REM) sleep, and symptoms of abnormal REM sleep, such as cataplexy, sleep paralysis, and hypnagogic hallucinations. ![]() Malicious abusers and/or continued abuse will lead to a ban.Ĭomments (especially top-level) consisting solely of anecdotes, jokes, memes, or otherwise off-topic remarks will be removed. Name-calling, ad hominems, racism, sexism, etc, will not be tolerated. If you would like to talk about careers in psychology, try /r/academicpsychology ![]() If you require participants for a survey, try /r/samplesize or our survey thread. Please do not post links to your own surveys. Perhaps why you found the content interesting or troubling, a critique of a study's methods, etc. We encourage users to make an initial comment in their submission thread. 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It is unethical for professionals to respond to such inquiries, and those not qualified shouldn't respond anyway. Please do not solicit psychological, psychiatric, or medical advice. About UsĪ Reddit community for the sharing and scientifically-based discussion of psychological material. We now have user flair! Please message the moderators if you'd like to add your degree. ![]() Note: Wayne Rasband has implemented similar changes to the built-in QuickTime movie player in ImageJ. Works under OS X and JVM 1.4+ and QuickTime for Java 6.1+. Original code by Wayne Rasband updated by Jeff Hardin for newer implementations of QTJ. QuickTime plugins available on the ImageJ web siteĭescription: This plugin played a QuickTime movie in a window with a standard movie controller. (d) May 2014: New versioning of the JVM and QuickTime necessitated an update for newest Mavericks (Mac OS X 10.9) machines. This means that for QTJava calls to function after updating to QuickTime for Windows 7.2 or higher, you must manually replace the QTJava.zip file associated with each older JVM. Apple's automatic update software for QuickTime only updates the QTJava.zip file associated with the newest version of the Java Virtual Machine installed. 2007: The latest update to QuickTime (7.2) can result in non-functional QuickTime for Java when a Windows machine has more than one version of the Java Runtime Environment (JRE) or the Java Development Kit (JDK). Downloading the QuickTime 7.2 updater as a standalone application at and reinstalling the QuickTime 7.2 update seems to fix this problem on the occasional machine I have encountered that displays this behavior. The latter overwrites some newer QTJ files that are installed as part of the QuickTime 7.2 update. 2007: The latest update to QuickTime (7.2) can result in non-functional QuickTime for Java when a Mac was updated first using the QuickTime 7.2 updater and then the OS X 10.4.10 combined updater. In addition to the book, Chris is a really cool guy and incredibly helpful to the QuickTime for Java developer community. An invaluable resource is Chris Adamson's book, QuickTime for Java: A Developer's Notebook (O'Reilly). I have rewritten a ton of code to allow my plugins to work on newer Macs. (a) Changes to the underlying architecture of QuickTime for Java broke many pieces of code under Mac OS X when using JMV 1.4+ and QTJ 6.1+. Additional instructions can be found here on the ImageJ web site. Windows users must install QuickTime 7 and copy QTJava.zip to the Java extensions folder (ImageJ\jre\lib\ext). Requires both QuickTime and QuickTime for Java. (3) QuickTime plugins require that QuickTime for Java (QTJ) is installed on your computer. The 4d_Plugins.jar file has been updated. Try the most recent versions of the plugins on this site if you are having trouble. (3) July 2011: Recent Java updates required changes to the version checking code in these plugins. ![]() (2) OS X Yosemite and later no longer does an install of QuickTime for Java. Quicktime for Java does not work at all on Windows systems running in 64-bit mode. ![]() This means that you must be running ImageJ in 32-bit mode. It does not function on 64-bit installations of ImageJ. (1) Quicktime for Java has long been deprecated by Apple. Wayne is a tireless servant of the biomedical imaging community. Thanks to Wayne Rasband (NIH) for writing the base code for ImageJ, and for hosting and annotating plugins. Many Quicktime plugins for ImageJ can be found on the ImageJ plugins page at the ImageJ website. ![]() Soft & gummy fruit flavored candy full of authentic juicy flavor you'll feel good about. BLACK FOREST GUMMY BEARS: Black Forest gummy bears are for kids & kids at heart.Black Forest Organic Candy, Gummy Bears, 65 Count, 0.8 Oz. GET YOUR GUMMY ON: From gummy bears to gummy worms, fruit snacks to sour heads, Black Forest candy is the perfect sweet snack to add flavor to your day. Black Forest Mini Gummy Bears 5.5 Oz Pack Of 2 6 Fruit Flavors Strawberry, Apple, Pineapple, Lemon, Cherry And Orange Made With Real Fruit Juice Fat Free And Gluten Free So Good And Juicy Gummy Brand: Black Forest.Made with real fruit juice, fat-free & gluten-free, each little gummy bear is as delicious as the last & the resealable bag keeps them fresh. SO GOOD: You know 'em, love 'em, now get your hands on some Black Forest Gummy Bears. Black Forest Organic Gummy Bears Candy, 8 Ounce, Pack of 6, Assorted Flavors and Colors. TASTE THE DIFFERENCE: What makes Black Forest gummies, fruit chews, & fruit snacks so good? Our classic & organic snacks have real fruit juice flavors, so each gummy bear, chew, or fruit snack is soft, chewy, & fruity.BLACK FOREST ORGANIC GUMMY BEARS: Black Forest organic gummy bears are for kids & kids at heart.Best Sellers Rank: 674 in Grocery & Gourmet Food ( See Top 100 in Grocery & Gourmet Food) 15 in Gummy Candies. GET YOUR ORGANIC CANDY ON: From coloring to flavoring, our organic gummies & organic fruit-flavored chews are USDA certified organic candy-we mean it! Plus, organic gummies are certified gluten-free! Package Dimensions : 11.81 x 7.95 x 5 inches 3 Pounds.Add a moment of fun to your day with Black Forest candy, whether you treat yourself or share with others. Black Forest Gummy Bears Back to School Candy, 1. Sour 0.5 Ounce (Pack of 5) 4.4 out of 5 stars 178. SO JUICY, JA! You'll love the juicy goodness of Black Forest gummies and fruit snacks. Black Forest Organic Gummy Bears, School Candy, 0.8 Ounce Pouches, 65 Count.Each organic gummy bear is yummy as the first. 2698 (0.34/Ounce) Save more with Subscribe & Save. ![]() SO GOOD: You know 'em, love 'em, get your hands on 'em! Made with real fruit juice, Black Forest Organic Gummy Bears are fat-free & gluten-free. Black Forest Classic Gummy Bears - 6 Fruity Flavors Made with Real Fruit Juice - Bulk Pack (Classic, 5 Pound) Classic 5 Pound (Pack of 1) 94. Grab a pack of these Black Forest Organic Gummy Bears, 0.8 oz, 65 Count and chew your way through deliciously fruity flavors like Orange, Apple, Cherry. TASTE THE DIFFERENCE: What makes Black Forest gummies, fruit chews, & fruit snacks so good? Our classic & organic snacks have real fruit juice, so each gummy bear, chew, or fruit snack is soft, chewy, & fruity. The latter is commonly measured in W⋅sr −1⋅m −2⋅nm −1. Radiance of a surface per unit frequency or wavelength. Watt per steradian per square metre per hertz ![]() This is sometimes also confusingly called "intensity". Radiant flux emitted, reflected, transmitted or received by a surface, per unit solid angle per unit projected area. The latter is commonly measured in W⋅sr −1⋅nm −1. Radiant intensity per unit frequency or wavelength. Radiant flux emitted, reflected, transmitted or received, per unit solid angle. The latter is commonly measured in W⋅nm −1. Radiant flux per unit frequency or wavelength. This is sometimes also called "radiant power", and called luminosity in Astronomy. Radiant energy emitted, reflected, transmitted or received, per unit time. Unlike power density, radiant intensity does not depend on distance: because radiant intensity is defined as the power through a solid angle, the decreasing power density over distance due to the inverse-square law is offset by the increase in area with distance. Radiant intensity, denoted I e,Ω ("e" for "energetic", to avoid confusion with photometric quantities, and "Ω" to indicate this is a directional quantity), is defined as I e, Ω = ∂ Φ e ∂ Ω, Mathematical definitions Radiant intensity In radio-frequency engineering, radiant intensity is sometimes called radiation intensity. Radiant intensity is distinct from irradiance and radiant exitance, which are often called intensity in branches of physics other than radiometry. m −1)-commonly the watt per steradian per nanometre ( W.Hz −1) and that of spectral intensity in wavelength is the watt per steradian per metre ( W. ![]() The SI unit of radiant intensity is the watt per steradian ( W/sr), while that of spectral intensity in frequency is the watt per steradian per hertz ( W In radiometry, radiant intensity is the radiant flux emitted, reflected, transmitted or received, per unit solid angle, and spectral intensity is the radiant intensity per unit frequency or wavelength, depending on whether the spectrum is taken as a function of frequency or of wavelength. For other measures of electromagnetic radiation, see Light intensity (disambiguation). For ionizing radiation, see Radiation flux. ![]() IV.Potential for skin surface distention or movement ![]() The more active the patient, the higher the adhesion required.Bulky dressings require high conformability and may require greater adhesion.Other support (e.g., sutures, tunneling).Some tapes are less gentle but are used for high initial adhesion, high long-term adhesion and high strength of backing.Ĭorticosteroids, chemotherapy malnourished).Gentle tapes with higher adhesion may be used without increasing the risk of skin trauma if properly applied and removed.Strength of adhesion and backing may be more important than gentleness.The more critical the tubing/dressing, the higher the adhesion required.3M Microfoam tape has a recommended shelf life of three years under these conditionsĬonsiderations While Choosing A Tape For Tube Or Dressing Secural:.It is recommended that 3M surgical tapes be stored under normal conditions within the temperature range of 59 – 86 degrees F (15 – 30 degrees C).Warm cycle aeration (temperature not to exceed 55 degrees C) for a minimum 20 hour cycle before use.EtO sterilized warm cycle 55 degrees C (130-145 degrees F), minimum 1 hour exposure time (50% RH - 600 mg/liter, or equivalent).Tape sealed in appropriate sterilization pouch or wrapper.glass, stainless steel, silicone-treated paper. Strips of medical foam tape arranged over a suitable release surface, e.g.How To Sterilize 3M Microfoam?The following method was tested and proven reliable for sterilization and stable adhesion performance, with ethylene oxide residuals well within U.S. Keep tape close to skin surface and slowly pull tape back. Remove tape in direction of hair growth.Loosen 3M Microfoam Surgical Tape ends.This may induce skin trauma in the form of blistering or skin tearing. Never apply Microfoam tape under tension.This will ensure the tape stays in place. Optimize adhesion by firmly rubbing or pressing the tape backing.Apply the tape evenly by positioning and pressing down from the center towards the edges.Apply 3M Microfoam Surgical Tape evenly to clean, dry surface.How To Use 3M Surgical Tape? 3M Application Instructions: 3M Tape can be used to secure bulky dressingsģM Microfoam - Tips For Trouble Free TapingģM Microfoam Tape - Solutions For Dressing And Device Securement.Post-operative compression and pressure dressings.Cardiovascular/angio sites, breast biopsies and surgical sites.Securing dressings on sites where movement is likely such as over joints and other challenging areas. ![]()
![]() Do not drive or operate machinery until you know how this medicine will affect you. Your ability to stay alert or to react quickly may be impaired by this medicine. Please speak with your doctor to understand the risks and benefits associated with this medicine.ĭo not use the medication any more than instructed. Some patients taking this medicine have experienced serious side effects. If you notice difficulty breathing, weight gain, or swelling of your legs or ankles, let your doctor know right away. Some patients with weak hearts may have worsening of symptoms. Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Talk to your doctor about the risks and benefits. Keep all appointments for medical exams and tests while on this medicine.ĭuring pregnancy, this medicine should be used only when clearly needed. Please speak with your healthcare provider or pharmacist. ![]() Pain or fever reducers may relieve some side effects. Tell your doctor if symptoms do not get better or if they get worse. Speak with your doctor or pharmacist before starting or stopping any medicine. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Tell your health care providers about all medicines taken. If you miss a dose, contact your doctor for instructions.ĭrug interactions can change how medicines work or increase risk for side effects. It is important that you keep taking each dose of this medicine on time even if you are feeling well. Tell your doctor if you have ever had an allergic reaction to latex. Choose a location at least 1 inch from the last injection. Using medicine before bedtime may lessen side effects.ĭo not inject into skin that is red, swollen or itchy.Ĭhange the location of the injection each time. Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely. If frozen, throw away.ĭiscard unused medicine after 12 hours at room temperature.ĭiscard any remaining medicine after your dose is given. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it. The liquid should be clear and colorless.Ĭheck the medicine before each use. If you have any questions, talk to your doctor, nurse, or pharmacist. Read and make sure you understand the instructions for measuring dose and using syringe. Please ask your doctor, nurse or pharmacist for the correct places on your body where this medicine can be injected.
![]() Today, it is regarded not only as a seminal work of science fiction but as one of the defining films of the 20th century. After the premiere, director Stanley Kubrick removed about 19 minutes worth of scenes and made a few changes: Some shots from the 'Dawn of Man' sequence were removed and a new scene was inserted where an ape pauses with the bone it is about to use as a tool. The film went on to win an Oscar for Best Visual Effects and numerous other awards. The film originally premiered at 160 minutes. Scenes in space are completely silent, reflecting the. ![]() Kubrick suggested that the film is about man’s relationship to the universe, an explanation of frustrating vagueness. Lead actor Keir Dullea estimated that he saw 250 people walk out of the premier, while Clarke reported hearing a studio executive remark, “Well, that’s the end of Stanley Kubrick.” Some reviewers agreed, calling the film “plodding,” “immensely boring,” and even “a disaster.” Many reviews were glowing, however – Roger Ebert gave it four stars, while Charles Champlin of The Los Angeles Times called it the “ultimate statement of the science fiction film.” Audiences seemed to agree with Champlin, flocking to the film upon its release and creating such demand that many American theaters screened it regularly for over a year. The ideas expressed in 2001: A Space Odyssey are interesting, but critics overstate their case when they behave as if the film is unusually profound or philosophical. scenes from Stanley Kubricks 2001: A Space Odyssey (1968).Original trailer: https:/. ![]() Today, few would argue against the greatness of 2001, but on the night of its debut Kubrick felt he had failed. A side-by-side comparison of the first Barbie (2023) teaser trailer vs. The movie screened at the theater on Minot AFB in North Dakota where my. Filming required the construction of a giant centrifuge to serve as the spaceship’s interior and numerous expensive visual effects, including a groundbreaking psychedelic sequence near the end of the film so complex that staff referred to it as the “Manhattan Project.” Kubrick is said to have removed over 15 minutes from the final cut, which nonetheless ran well over 2 hours. I can still remember to this day seeing 2001: A Space Odyssey for the first time. The film does feature a coherent plot, involving two scientists and a highly-intelligent computer sent to investigate a mysterious event near Jupiter, but several scenes-including the film’s now-legendary opening, which seems to depict hominids learning to use tools after the appearance of a mysterious monolith-are surreal and highly open to interpretation. Leonard played Andre Smyslov, a Russian scientist trying to discover the real goings on at the mo. He became determined to make one, using the sci-fi story The Sentinel as source material and enlisting its author, Arthur C. Leonard Rossiters scenes from the Stanley Kubrick classic. Strangelove had been popular with audiences and critics alike, was intrigued by science fiction but felt the genre rarely produced interesting films. Stanley Kubrick’s 2001: A Space Odyssey debuts in theaters on April 6, in 1968. The race time is an adjusted estimation that takes into account that faster paces cannot be maintained for longer than slower paces. The calculator will also use this information to estimate your race time and compare it to other runners. Thanks to it, you don't have to convert the units in order to find out how much time you need to cover a kilometer, meter, mile, or yard. The calculator will automatically estimate your average speed (km/h) and pace in a variety of units. You can use the running pace calculator not only when you jog but also when you cycle, skate, or do any other sport which requires covering some specific distance. It is particularly useful for people who exercise regularly. The pace calculator is a tool that counts your pace and speed on the basis of the distance you've done and the time you've done it in. ![]() That's why it's worth using the pace calculator, which can save us from any mistakes. If we move 50 km within 1 hour, our:Īlthough these two equations are not very complicated, it's easy to mix them up. Pace (sec/km) = time (sec) / distance (km). In order to count speed and pace all by yourself, you need 2 formulas: Pace is given in units of time per unit of distance, whereas speed is the distance over time. As a result, we use different measurement units to express these values. By this, we mean that by counting pace, you find how much time you need to cover a particular distance, while speed is an indicator of the number of kilometers you are able to cover within one hour. ![]() Although both values express similar information, they are the reverse of each other. Firstly, let's make it clear what the difference between pace and speed actually is. |
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